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iSTREEM® Relevant Publications

McDonough, K., Csiszar, S.A., Fan, M., Kapo, K., Menzies, J. and Vamshi, R. 2021. Spatial modeling framework for aquatic exposure assessments of chemicals disposed down the drain: Case studies for China and Japan. Integr Environ Assess Manag. 2021 July 31. DOI: 10.1002/ieam.4506

Burns, E.E., Csiszar, S.A., Roush, K., and Davies, I.A. 2021. National-scale down-the-drain environmental risk assessment of oxybenzone in the United States. Integr Environ Assess Manag. 2021 Apr 29. DOI: 10.1002/ieam.4430


Holmes, C.M., Dyer, S.D., Vamshi, R., Maples-Reynolds, N., and Davies, I.A. 2020. A National-Scale Framework for Visualizing Riverine Concentrations of Microplastics Released from Municipal Wastewater Treatment Incorporating Generalized Instream Losses. Environ Toxicol Chem. 2020 Jan;39(1):210-219. DOI: 10.1002/etc.4610


Ferrer, D.L. and Deleo, P.C. 2017. Development of an in-stream environmental exposure model for assessing down-the-drain chemicals in Southern Ontario. Water Quality Research Journal. In Press. Available Online 26 September 2017. DOI: 10.2166/wqrj.2017.019

McDonough, K., Casteel, K., Zoller, A., Wehmeyer, K., Hulzebos, E., Rila, JP., Salvito, D., and Federle, T. 2017. Probabilistic determination of the ecological risk from OTNE in aquatic and terrestrial compartments based on US-wide monitoring data. Chemosphere, Volume 167, January 2017, Pages 255-261. DOI: 10.1016/j.chemosphere.2016.10.006

Kapo, K.E., Paschka, M., Vamshi, R., Sebasky, M., and McDonough, K. 2017. Estimation of U.S. sewer residence time distributions for national-scale risk assessment of down-the-drain chemicals. Science of The Total Environment, Volume 603, 2017, Pages 445-452. DOI: 10.1016/j.scitotenv.2017.06.075

Posthuma, L., Dyer, S.D., de Zwart, D., Kapo, K., Holmes, C.M., and Burton, G.A., Jr. 2016. Eco-epidemiology of aquatic ecosystems: Separating chemicals from multiple stressors. Science of The Total Environment, Volume 573, 15 December 2016, Pages 1303-1319. DOI: 10.1016/j.scitotenv.2016.06.242


Kapo, K. E., DeLeo, P. C., Vamshi, R., Holmes, C. M., Ferrer, D., Dyer, S. D., Wang, X. and White-Hull, C. 2016. iSTREEM®: An approach for broad-scale in-stream exposure assessment of "down-the-drain" chemicals. Integr Environ Assess Manag, 12: 782–792. DOI: 10.1002/ieam.1793

Kapo, K.E., McDonough, K., Federle, T., Dyer, S., and Vamshi, R. 2015. Mixing zone and drinking water intake dilution factor and wastewater generation distributions to enable probabilistic assessment of down-the-drain consumer product chemicals in the U.S. Science of The Total Environment, Volumes 518–519, 15 June 2015, Pages 302-309. DOI: 10.1016/j.scitotenv.2015.02.105

Diamond, J., Munkittrick, K., Kapo, K. E. and Flippin, J. 2015. A framework for screening sites at risk from contaminants of emerging concern. Environ Toxicol Chem, 34: 2671–2681. DOI: 10.1002/etc.3177


Cowan-Ellsberry, C., Belanger, S., Dorn, P., Dyer, S., McAvoy, D., Sanderson, H., Versteeg, D., Ferrer, D., and Stanton, K. 2014. Environmental Safety of the Use of Major Surfactant Classes in North America. Crit Rev Environ Sci Technol. 2014 Sep;44(17):1893-1993. DOI: 10.1080/10739149.2013.803777

Mudge, S.M. and DeLeo, P.C. Estimating Fatty Alcohol Contributions to the Environment from Laundry and Personal Care Products using a Market Forensics Approach. Environ. Sci.: Processes Impacts, 2014, Advance Article, 08 Oct 2013. DOI: 10.1039/C3EM00418J

Simonich, S. M., Sun, P., Casteel, K., Dyer, S., Wernery, D., Garber, K., Carr, G. and Federle, T. 2013. Probabilistic analysis of risks to us drinking water intakes from 1,4-dioxane in domestic wastewater treatment plant effluents. Integr Environ Assess Manag, 9: 554–559. DOI: 10.1002/ieam.1448

Sanderson, H., van Compernolle, R., Dyer, S.D., Price, B.B., Nielsen, A.M., Selby, M., Ferrer, D., and Stanton, K. Occurrence and risk screening of alcohol ethoxylate surfactants in three U.S. river sediments associated with wastewater treatment plants. Science of The Total Environment, Volumes 463–464, 1 October 2013, Pages 600-610, ISSN 0048-9697. DOI: 10.1002/ieam.1448.

Laurenson, J.P., Bloom, R.A., Page, S., and Sadrieh, N. Ethinyl Estradiol and Other Human Pharmaceutical Estrogens in the Aquatic Environment: A Review of Recent Risk Assessment Data. AAPS J (2014) 16: 299. DOI: 10.1208/s12248-014-9561-3

Federle, T., Sun, P., Dyer, S., and Kiel, B. Probabilistic assessment of environmental exposure to the polycyclic musk, HHCB and associated risks in wastewater treatment plant mixing zones and sludge amended soils in the United States. Science of the Total Environment, Volume 493, 15 September 2014, Pages 1079-1087. DOI: 10.1016/j.scitotenv.2014.03.058

Grill, G., Khan, U., Lehner, B., Nicell, J., and Ariwi, J. Risk assessment of down-the-drain chemicals at large spatial scales: Model development and application to contaminants originating from urban areas in the Saint Lawrence River Basin. Science of The Total Environment, Volume 541, 15 January 2016, Pages 825-838, ISSN 0048-9697. DOI: 10.1016/j.scitotenv.2015.09.100

Rice, J., Wutich, A., and Westerhoff, P. Assessment of De Facto Wastewater Reuse across the U.S.: Trends between 1980 and 2008. Environmental Science & Technology 2013 47 (19), 11099-11105. DOI: 10.1021/es402792s

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